Evaluation of Zebrafish as a Model to Study the Pathogenesis of the Opportunistic Pathogen Cronobacter Turicensis

http://www.leica-microsystems.com/science-lab/hyvolution/evaluation-of-zebrafish-as-a-model-to-study-the-pathogenesis-of-the-opportunistic-pathogen-cronobacter-turicensis/

Application example of HyVolution Super-Resolution – Bacteria belonging to the genus Cronobacter spp. have been recognized as causative agents of life-threatening systemic infections, primarily in premature, low-birth weight and/or immune-compromised neonates. Knowledge remains scarce regarding the underlying molecular mechanisms of disease development. In this study, we evaluated the use of a zebrafish model to study the pathogenesis of Cronobacter turicensis LMG 23827T, a clinical isolate responsible for two fatal sepsis cases in neonates.

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